In February 2026, the World Health Organization released the latest edition of Consolidated guidance on hepatitis B and C prevention, testing, treatment, service delivery and monitoring: An implementation handbook for a public health approach. This guidance integrates more than 80 evidence-based recommendations and good practice statements issued from 2015 to 2025, and it is the first handbook that combines all hepatitis B, C and D guidelines into a single reference document. The guideline centers around five core areas of prevention, testing and diagnosis, treatment and care, simplified services, and strategic information to simplify and expand access to interventions through public health approaches, so as to accelerate the achievement of the global goal of eliminating the public health threat of viral hepatitis by 2030. This article summarizes the core recommendations and implementation considerations in the handbook.