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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2011
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Therapy advances in primary biliary cirrhosis

  • Received Date: 2011-02-09
  • Published Date: 2011-06-20
  • Primary biliary cirrhosis (PBC) is a chronic intrahepatic cholestatic disease.Ursodeoxycholic acid (UDCA) is the only safe and effective drug for the treatment of PBC proven by randomized controlled clinical trials.Favorable long-term effects of UDCA are observed in patients with good biochemical response after one year treatment.There is currently no consensus on how to treat patients with a suboptimal biochemical response to UDCA.Liver transplantation is the only therapeutic option for end-stage patients.

     

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