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Volume 42 Issue 6
Jun.  2026
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Article Navigation >  Journal of Clinical Hepatology  > 2026  >  42(6): 1469-1474

Assessment of the severity and prognosis of acute pancreatitis

DOI: 10.12449/JCH260634
  • 1.

    The Second Clinical Medical College of Lanzhou University，Lanzhou 730030，China

  • 2.

    Department of Emergency Medicine，The Second Hospital of Lanzhou University，Lanzhou 730030，China

Research funding:

National Natural Science Foundation of China (82260135)

More Information
  • Corresponding author: LI Peiwu， lipeiw@lzu.edu.cn （ORCID： 0000-0003-3127-930X）
  • Received Date: 2025-10-16
  • Accepted Date: 2025-11-28
  • Published Date: 2026-06-25
    Abstract
  • Acute pancreatitis （AP） often has an acute onset， and although most cases are self-limiting， there is still a risk of rapid deterioration， posing a serious threat to the lives of patients. Currently， traditional assessment tools such as clinical scoring systems and serum biomarkers are widely used to determine disease severity and prognosis. To enhance the accuracy of assessment， combined detection strategies integrating different scores and biomarkers are often used in clinical practice； however， there are still certain limitations such as insufficient specificity， limited early sensitivity， and a lack of consistent cut-off values. Therefore， current studies are actively exploring novel biomarkers with superior specificity and sensitivity and continuously optimizing their combined application strategies. This article summarizes the current application status of traditional assessment tools and reviews the research advances in novel biomarkers.

     

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