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Volume 41 Issue 5
May  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(5): 948-953

Role and regulatory mechanism of heme oxygenase in metabolic associated fatty liver disease

DOI: 10.12449/JCH250522
  • 1.

    Spleen，Stomach and Hepatobiliary Department，The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450000，China

  • 2.

    School of Nursing，Henan University of Chinese Medicine，Zhengzhou 450046，China

  • 3.

    Shandong College of Traditional Chinese Medicine，Yantai，Shandong 264100，China

Research funding:

Special Project of Key R & D and Promotion in Henan Province (232102310450);

Henan Province Chinese Medicine Scientific Research Special Project (2022JDZX089);

Henan Provincial Medical Science and Technology Public Relations Programme (RKX202201009);

Henan Provincial Social Sciences Planning Project (2024XWT005)

More Information
  • Corresponding author: WANG Lei， hyzhaohushan@163.com （ORCID： 0009-0002-8488-5741）
  • Received Date: 2024-09-07
  • Accepted Date: 2024-11-08
  • Published Date: 2025-05-25
    Abstract
  • This article systematically reviews the role and relationship of heme oxygenase （HO） in the pathogenesis of metabolic associated fatty liver disease （MAFLD） and discusses the biological function of HO， its expression in the liver， its association with lipid metabolism， and its regulatory role in inflammatory reaction and oxidative stress， in order to reveal the potential therapeutic targets and mechanism of HO in MAFLD and provide new perspectives and directions for future treatment strategies.

     

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