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Volume 41 Issue 4
Apr.  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(4): 793-800

The mechanism of effective traditional Chinese medicine components and prescriptions in treatment of chronic pancreatitis by intervening against pancreatic stellate cells

DOI: 10.12449/JCH250429
  • 1.

    Graduate School，Heilongjiang University of Chinese Medicine，Harbin 150040，China

  • 2.

    Institute of Traditional Chinese Medicine，Heilongjiang University of Chinese Medicine，Harbin 150040，China

Research funding:

The Central Government of Provincial Undergraduate Universities in Heilongjiang Province Supports the Reform and Development of Local Universities and Funds for Talent Training Projects (2021ZYQGLG001);

Heilongjiang University of Traditional Chinese Medicine Excellent Innovative Talents Support Program Project (2018RCL13)

More Information
  • Corresponding author: LU Fang， lufang_1004@163.com （ORCID： 0000-0001-7210-3285）; LIU Shumin， keji-liu@163.com （ORCID： 0000-0002-4812-3494）
  • Received Date: 2024-07-17
  • Accepted Date: 2024-08-21
  • Published Date: 2025-04-25
    Abstract
  • Chronic pancreatitis （CP） is a chronic disease characterized by recurrent inflammation and progressive damage to pancreatic tissue， and its deterioration may increase the risk of pancreatic cancer in patients with CP， which seriously threatens the health of patients with CP. In recent years， studies on the pathogenesis of CP have mostly focused on the activation of pancreatic stellate cells （PSCs） and its role in pancreatic fibrosis. This article elaborates on the mechanism of action of PSCs in CP， summarizes the current status of research on effective traditional Chinese medicine components and prescriptions for intervention of PSCs in the treatment of chronic CP， and proposes the future research directions for effective traditional Chinese medicine components and prescriptions， so as to provide a reference for the clinical treatment of CP patients in the future.

     

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