《2025年代谢功能障碍相关脂肪性肝病和脂肪性肝炎全球共识建议》摘译
DOI: 10.12449/JCH250809
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:刘爱芳负责文章翻译;邹波、杨文龙、罗磊负责拟定写作思路,指导撰写文章并文章校订;张晶负责审校及修改稿件。
An excerpt of global consensus recommendations for metabolic dysfunction-associated steatotic liver disease and steatohepatitis (2025)
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摘要: 2025年4月,《代谢功能障碍相关脂肪性肝病和脂肪性肝炎全球共识建议》在Gastroenterology在线发布,该指南主要就代谢功能障碍相关脂肪性肝病(MASLD)筛查必须遵循的步骤、使用非侵入性检查对MASLD进行风险分层、合并症的治疗以及最近获批的瑞美替罗治疗代谢功能障碍相关脂肪性肝炎这些存在分歧的领域达成全球共识,覆盖了当下MASLD管理的最热议题。本文对该共识建议中主要内容进行摘译。Abstract: In April 2025, Global consensus recommendations for metabolic dysfunction-associated steatotic liver disease and steatohepatitis was published online in Gastroenterology. These recommendations address the areas with significant divergence, such as metabolic dysfunction-associated steatotic liver disease (MASLD) screening steps, the use of noninvasive tests for risk stratification, management of comorbidities, and the recent advances in resmetirom for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), covering the most debated topics in current MASLD management. This article makes an excerpt of the main contents in these consensus recommendations.
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[1] YOUNOSSI ZM, ZELBER-SAGI S, LAZARUS JV, et al. Global consensus recommendations for metabolic dysfunction-associated steatotic liver disease and steatohepatitis[J]. Gastroenterology, 2025. DOI: 10.1053/j.gastro.2025.02.044.[ Epub ahead of print] -

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