《2025年欧洲肝病学会临床实践指南： 肝外胆管癌的管理》摘译

《2025年欧洲肝病学会临床实践指南：肝外胆管癌的管理》摘译

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：丁宗仁负责翻译；黄尧、曾永毅负责审校。

详细信息

Department of Hepatobiliary Surgery，Mengchao Hepatobiliary Hospital of Fujian Medical University，Fuzhou 350025，China

摘要: 近年来，胆管癌（CCA）的影像学诊断、分子图谱分析及系统治疗取得了显著进展。尽管如此，早期检测、精准分类和有效管理仍面临诸多挑战。鉴于CCA亚型间的显著差异及最新研究进展，欧洲肝病学会制定了基于证据的肝外胆管癌，包括肝门部和远端胆管癌的管理推荐意见。本指南特别强调了精准分类系统的需求、新兴分子研究的整合，以及反映真实临床场景的实用诊断和治疗策略。
- 胆管肿瘤 /
- 欧洲 /
- 诊疗准则
Abstract: In recent years， significant progress has been made in the radiological diagnosis， molecular profiling， and systemic therapy of cholangiocarcinoma（CCA）. Nevertheless， there are still many challenges in early identification， precise classification， and effective management. Given the marked heterogeneity between CCA subtypes and the recent research advances， the European Association for the Study of the Liver has developed evidence-based management recommendations for extrahepatic CCA， covering both perihilar and distal subtypes. This guideline particularly emphasizes the need for precise classification systems， the integration of emerging molecular studies， and practical diagnostic and therapeutic strategies reflecting real-world clinical scenarios.
- Bile Duct Neoplasms /
- Europe /
- Practice Guidelines

[1]	European Association for the Study of the Liver. EASL Clinical Practice Guidelines on the management of extrahepatic cholangiocarcinoma[J]. J Hepatol, 2025, 83( 1): 211- 238. DOI: 10.1016/j.jhep.2025.03.007.